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<h2>PLANTAIN AS A STYPTIC.</h2>
<p>[Footnote: Read at the meeting of the Amer. Pharm. Assoc.]</p>
<h3>By J.W. COLCORD.</h3>
<p>Several articles during the past few months, copied from English
pharmaceutical journals, calling attention to the styptic
properties of plantain leaves--Plantago major--having attracted my
attention, I determined to try a few experiments when opportunity
offered. Having a shiftless neighbor whose yard produced a
bountiful crop of the article, I was easily able to secure an
abundant supply for my experiments. Believing that better results
would be obtained from fresh plants than from dried, I expressed
the juice from them by means of an "Enterprise" mill, obtaining
about 16 fluid ounces of juice from 3 pounds of leaves. The juice
was of a light green color, very turbid, evidently caused by a
large amount of chlorophyl. Setting aside 4 ounces of the filtered
liquid for further experimenting, I packed the residue from the
press into a conical glass percolator and exhausted with dilute
alcohol, evaporating the percolate in a water-bath to two ounces,
mixing with the 12 ounces of expressed juice and adding 2 ounces of
alcohol. This preparation, which I call a fluid extract, represents
virtually equal parts by weight of the dried plants. It is of a
dark brown color with a marked odor of the recent plant, and so
far, after standing three months undisturbed on my shelves, shows
no sign of precipitation.</p>
<p>My next experiment was a mixture of equal quantities of the
expressed juice with glycerin. At the present time, after standing
three months, the mixture is clear and bright, with no sign of
precipitation. This, I think, promises to be the most efficient
preparation, and will prove valuable as an injection in the
treatment of leucorrhoea, hemorrhages, and similar disorders.</p>
<p>Experiment number three was made with equal parts of the juice
and alcohol, and number four with three parts of the juice with one
part of alcohol.</p>
<p>In a short time a precipitate was observed in both samples in
about equal proportions, and was removed about one month after
making by filtering through paper, and neither has shown signs of
precipitation since, and continue bright, clear, light-brown
liquids.</p>
<p>Of their therapeutic value as styptics, I have not had
sufficient trial to form an opinion, although, as far as I can
judge, they have proved satisfactory. While writing this article, a
cook from a neighboring restaurant, with a finger sliced off in a
potato slicer, exposing the bone, came in for treatment. Having
bandaged I applied the glycerate, which soon stopped the profuse
bleeding, giving her a small bottle of it to apply subsequently. I
asked her to report to me in two or three days, and, on reporting,
I found a healthy granulation presenting. Its styptic properties
are undoubtedly due to tannic acid, as all the tests I have been
able to make prove this to be the case. The readiness with which it
can be obtained in the summer renders it a valuable adjunct,
undoubtedly, to the materia medica of the country practitioner or
housewife for stopping hemorrhages in simple wounds.</p>
<p>The bruised leaves applied directly usually prove sufficient for
the purpose; as to whether it will prove sufficiently valuable to
add to our list of pharmaceutical preparations will require longer
and more extended experiment.--<i>New Remedies</i>.</p>
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